The search for our identities—where we came from, what we’re made of—is a unifying human experience, and our collective fascination with ourselves as individuals has fueled a booming industry around personal DNA testing. Once difficult and expensive even for the most technologically advanced labs, genetic testing is fast becoming a cheap and easy consumer product. More than 12 million people have had their DNA tested by different companies, and that number is expected to grow substantially in the next few years. With a little spit and 200 dollars, you can find out your risk for everything from cystic fibrosis to lactose intolerance.
What Can I Find Out with my DNA test?
Any type of genetic testing, from the consumer-based kits that anyone can buy to the versions that doctors order, can only glean so much information from your DNA. Medical conditions like cancer and heart disease are complex and not likely to be traced to a single aberration in DNA. However, there are some genetic variants that do link to a stronger chance for certain conditions. In those cases, having the genetic change doesn’t ensure that you will develop the condition, but could mean that you have a higher chance of getting the disease.
To sort that out, a Spanish company has created its own unique chip that is able to identify more than 360 information items in the DNA, among which is the susceptibility to polygenic or complex diseases, the diagnosis of monogenic diseases, pharmacogenetic information and phenotypic traits. Thanks to this incorporation of exact biomarkers, the result of the TellmeGen’s DNA test is a 28% more accurate system, compared to than offered by other companies such as the american ‘23andMe’. This makes it a revolutionary DNA test because it offers the analysis of more items at a lower price. The goal of TellmeGen is to provide access to genetic information to people from anywhere in the world. In order to do so, they have developed a platform to store, interpret and update the genetic information when new mutations are discovered. TellmeGen is currently studying more than 555,000 mutations, and they provide this new and updated information at no additional cost.
How Does It Work?
After extracting DNA from your cheek swab or saliva sample, DNA testing companies search your DNA for certain genetic variants. The building blocks of DNA are chemical bases called nucleotides, which come in four varieties—A, T, C, and G (adenine, thymine, cytosine, and guanine, respectively). We have 3 billion pairs of these bases, so 6 billion letters in all, strung together in a sequence. Altogether, this genetic information is called your genome.
DNA testing companies determine which of the four letters is present at many locations in your genome. Much of the sequence is shared among humans, so the companies focus on specific letters that vary from person to person, known as single nucleotide polymorphisms (SNPs). Many SNPs have some biological relevance. For example, having one variant of a specific SNP near the gene OCA2, which codes for a protein believed to be involved in producing the dark pigment melanin, makes it much more likely you’ll have blue or green eyes. Other traits and even some diseases are also associated with certain SNPs, some more strongly than others.
The pioneering technology behind TellmeGen’s system is the genotyping chip, which is then analyzed in the sequencers of their many laboratories spread throughout Europe and Latin America. Thus, the system is based on scientific evidence and reaches 99.99% reliability. To get their DNA tested, all the user has to do is putting a sample of his saliva in the tube that arrives at home inside the TellmeGen Kit box and send it back to the company. You can get the DNA test on Amazon.com. Four to six weeks later, the client receives an electronic notification that his health map is already available online. In addition to the genetic information, each item in the genetic map is associated with the latest recommendations on health prevention. The users also have access to a free public forum where they can interact with medical professionals to interpret their results, and they can also hire the services of a specialist for a better interpretation of the results in an individual consultation.
How Much Does It Cost?
The idea of knowing our health’s risks in advance to be able to prevent diseases is always appealing, but the real question is: how much does a DNA test cost? TellmeGen wanted make genetic health maps affordable to everyone, and in order to do so they based their strategy on adjusting the costs. After years of previous study and analysis, they finally managed to launch TellmeGen DNA test kit, which reduces the average 3,500€ price to 199$, greatly improving the ratio items / price of any other market test.
Plus, the analysis offers four types of results in a single analysis for the same price: risk of the most common diseases, monogenic diseases, pharmacology and personal traits. In addition, in a few weeks ‘Ancestry’ will also be offered for the same price. Customers who used the kit prior to this will not have to pay more, as the results will automatically be updated for free.
Inventor of a liposuction technique, Dr. Dario Bazzano shares tips on cosmetic surgery
According to the American Society of Plastic Surgeons (ASPS), the percentage of cosmetic surgery performed in the United States between the years of 2000 and 2018 remained relatively constant. These include surgeries like breast augmentation and liposuction. On the other hand, less invasive procedures such as botox and chemical peels have increased 228 percent in this same period.
In face of such data, it seems that Americans are preferring an approach more orientated to aesthetic medicine, that is, techniques that are less invasive and therefore risky. But there’s good news: Dr. Dario Bazzano, an aesthetic surgeon with 17 years of experience and more than 4,000 operations performed, has invented and patented a technique of liposuction called “biolipospectrum.”
Less invasive and more efficient than the options more commonly available in the market, “biolipospectrum” allows the skin to contract more, reduces or eliminates bleeding (thus allowing a great percentage of fat to be eliminated) and offers a much quicker postoperative recovery time. In fact, the surgery takes only about two hours and is not very painful or invasive. According to Dr. Bazzano, patients could have the surgery on a Friday, for example, and Monday or at the latest Tuesday, they could be going back to work yet.
However, as experienced and serious as Dr. Bazzano is, there are other challenges he faces at work than the complexity of surgeries. The surgeon says that oftentimes, girls show up with retouched photos of themselves or even pictures of celebrities. Sometimes, says the doctor, the requests are even excessive and may indicate a distorted view of the patient over their own body. “In that case, professional seriousness demands refuse to perform the intervention,” he adds.
The most popular requests in the clinic include breast augmentations (reconstruction of the breast through a prosthesis) and liposculpture or lipofilling and abdominoplasty. “In short, everything related to the correction of body shapes,” adds Dr. Bazzano. After these two types of operations, there is also a lot of interest in blepharoplasty, which is the reconstruction of the inner part of the thighs.
But since these procedures involve surgery and relatively invasive techniques, what is the best way to choose the professional? Dr. Bazzano says that people can check publications and also take a look at photos of previous interventions performed by a professional, but beware of retouched photos. “They look better than the ‘raw’ photos, but these are nevertheless capable of showing the reality of the facts, as opposed to photos that are pleasing to the eye, but decidedly artificial,” advises the surgeon. Finally, Dr. Bazzano says that it is important that the patient trusts the doctor and that there is empathy between them, which means cosmetic procedures are not just about technique, but also about human relationships.
Benefits in the measurement of strength and speed exercises
Preparing and actual work are vital in day to day existence, regardless of whether for expert or novice competitors. For a right observing of how we are improving and arriving at various levels, there is the chance of estimating the speed and strength that we are acting in every daily schedule. Choices like Vitruve permit us to quantify the preparation, and today we will discuss the advantages that this implies for charting and playing out our schedules.
What is Vitruve?
The Vitruve training enconder is a device that unites the latest in estimation innovation with precision in terms of monitoring information about the space traveled and the movement time of an external load. By merging it with our activity program, it allows us to explicitly know how we are progressing based on the factors of strength, mechanical work, endurance or speed.
With the assistance of Vitruve, information and a fitness coach, we can additionally alter our active work schedules to benefit from them. Yet, taking these estimations additionally brings us different advantages when we train.
How linear encoders work?
Linear encoders are dynamometers that are used within the sports context to carry out direct and continuous measurements of the space traveled by an external load (bars, weights, dumbbells… among others), taking into account the time during which it occurs said displacement. Through a series of calculations, the device will provide you with a series of variables that will allow you to measure the performance of your exercise session, thus helping to evaluate the changes in strength that you may experience as your training progresses.
The results provided by linear encoders are characterized by very low errors, making these devices extremely useful tools for the most dedicated powerlifters. It must be taken into account, however, that the error that we can find in the results is derived from the inclination when lifting the free weights. In the event that we deviate the trajectory of the weight by 5 degrees, for example, the results would suffer an error of 0.38%.
These devices are an ideal investment for all those who seek to make the most accurate measurements possible on the evolution of their physical condition when undergoing training. The truth is that the degree of precision and guarantees provided by the numerous scientific studies that validate the results of linear encoders more than justify the purchase.
Vitruve encoder: affordable model with endless benefits
Despite the many advantages of using a linear encoder for physical exercise, it is true that some drawbacks can be mentioned at the same time that make us reconsider this purchase. These disadvantages disappear when we take into consideration the Vitruve brand of encoder, designed to solve some of the main problems that these products usually have.
First of all, we have to mention that the use of a normal linear encoder requires a laptop computer. However, the Vitruve encoder manages to work completely independently, making its use much more accessible by not forcing us to carry a laptop with us wherever we want to perform our training.
In return, the Vitruve device shows the calculated results through a display, information that can be complemented with what we get from synchronizing the encoder with our Android or iOS phone through the Vitruve app. In case it bothers you to rely on a mobile device, you should know that the data you have access to thanks to Vitruve’s display includes the calculations of average propulsive speed, maximum speed, repetition number and encoder battery.
Another concern that may arise before deciding to purchase this encoder is the minimum sensing distance. When we do a weight lifting exercise, it is possible that the encoder does not detect the effort made by not exceeding the minimum distance required for the device to detect a repetition. This is not a problem for the Vitruve encoder, as it includes an option to modify the centimeters you want it to detect in a repetition.
Thanks to the use of the Vitruve encoder you can experience a number of benefits, including an increase of up to 20% of the 1RM (maximum weight that can be lifted in a single repetition), reduced risk of injury by using the optimal load, increased explosiveness and reduction of up to 60% of the recovery time, among others.
Undoubtedly, Vitruve offers athletes a very valuable tool with which to get the most out of their strength training, obtaining very detailed information about their performance that will allow them to progress at a faster rate. If you also want to take advantage of all that the Vitruve encoder has to offer, don’t think twice. Taking into account all these advantages together with the fact that, compared to the rest of the competition, the price of the Vitruve encoder is much more affordable, the purchase decision becomes much more obvious.
Mitigating The Effects Of Harmful Health Issues
Self-care is very often seen as a proactive process, that is, in order to succeed in it, you need to perfect each day, to work out hard, to get perfect sleep, and to eat properly. Sure, you might not be able to live up to perfection in this way, but it is good to use that as a proper rule of thumb going forward.
That said, sometimes, we’re not in the right stage of our lives to just think that’s all we need. After all, if you’re managing a health condition, a habit that has harmed your health, or you’re suffering from the effects of health mismanagement over the years, it can be tough to return to that baseline and know how to go on from there.
Any self-care advice, then, is incomplete unless it properly understands this and leverages guidance to people just looking to improve, no matter what relative point they may currently occupy. Thankfully, there are ways to get the most out of this, and in this post, we hope to discuss how to mitigate the effects of harmful health issues so you can return to an appropriate normal:
Identify That Which Is Holding You Back
It’s good to figure out exactly what it is that’s holding you back, in its full scope. After all, we cannot make progress if we’re fooling ourselves, or haven’t fully understood the issue. For some people, this might mean collecting the courage to attend a medical checkup. After all, for some people, this can be a worrying process.
This is especially true as we get older, and the necessity for more regular medical checkups are required. Men in their 40s are usually known for being quite flimsy about having issues seen to, fearful of prospective health issues and what that might mean for their overall sense of robustness and wellbeing. That’s a generalization, however, as it’s true that anyone can experience health anxiety and want to delay facing that kind of clinical inspection to the degree that they can.
That said – it’s best to view this in its full scope. You might find that your drinking habits have gone unchecked for a small while, and you need to actually record how much you’re consuming and spending to understand how deep the problem lies. With the help of trusted relatives, friends and objectively noting that which is troubling us, we can come to a better understanding.
Ask For Help If Necessary
We can often think that harmful health issues must be dealt with in stern silence, but that’s not true at all. If you ask for it, help is out there. From relief programs to the simple guidance of a friend willing to take you to your checkups or meetings, you’d be surprised how many people can and will pull together to help you through a tough spot if needed. Asking them to do so can be the first step, be that attending drug rehab or physiotherapy sessions.
Find A Step-By-Step Recuperative Program
Finding a step-by-step recuperative program you can use to gain potential and increment your progress can be worthwhile in helping you avoid trying to do this all on your own. For instance, a weekly meeting with a therapist can be key towards managing old behaviors and building the new in its place.
Managing Quality of Life
It might not be that you can live the life you had before, but that’s not to say you should feel totally disconnected from the quality of life you deserve to lead. Through appropriate exercise, leveraging the support you’re entitled to, keeping optimistic, and engaging fully with a course of treatment or lifestyle guidance, as well as using the internet or support groups to discuss with people who actually understand, this process can be much more manageable, no matter your condition.
Believe In Better
Ultimately, your attitude will determine how well you make it through this process and reclaim your own potential. Sure, you should never be blamed for suffering an optimism hit once experiencing a real-life malady, such as becoming newly disabled with a condition, but it’s important to recognize that life is not over.
Believing in better and making do with the best of what you have, though it’s easy for us to type and harder for you to live, can be a great way of finding your renewed joy and lightening your spirit so that your condition becomes part of your life, not the defining factor of it. You would be amazed at how this intent can leverage results.
With this advice, we hope you can mitigate the effects of harmful health issues, using a range of practical steps, social aid, and motivational willingness. You’ve got this.
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