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Science is always helping to change and grow our understanding of the world. When a new drug is developed, it helps to ensure that the drug is vigorously tested before it’s allowed to be on the market. The tests, from lab tests to clinical trials, are designed to determine both the efficacy and the safety of any drug. Just like any other area of science, the methods and techniques used to approach this testing is changing and evolving all the time. Today, there are various advancements and trends that stand out as being helpful and make tests of new drugs and treatments more accurate and informative.

More Involved Patients

Clinical trials are used to help test new medications and treatments on people. Rather than treating the people participating in these trials as merely test subjects, there has been an increasing interest in placing the patient at the center. Patients are becoming more involved in the trials they participate in, able to carry out a lot of their own research, thanks to the internet. They also get involved with advocacy groups and support groups to discuss their medical conditions and treatments. Clinical trials can benefit from the insights these patients are able to provide. They can be used to help improve quality of life for patients, for example. Read more about it from http://www.biopharmadive.com/news/5-trends-changing-clinical-trials/437416/.

More Effective Testing in Animals

Although many people don’t like it, testing drugs on animal models is one of the best methods we have for developing a drug before it can be tested on humans. Rats and mice are some of the most common animals used. Although they have qualities that make them useful test subjects, they’re obviously not exactly like humans. However, new ways of creating “humanized” rodents makes them more useful. You can discover more at www. HeraBioLabs.com/technology/humanized-rodents. Essentially, tissues, cells, and genes can be humanized by replacing rodent material with human material. For example, human cells can be used to develop a human liver within a rodent.

Increased Use of Technology

Technology has been adopted in all industries and walks of life, but it can be particularly useful in different fields of science. Within drug development and testing, it can help with a wide variety of things. One area where it’s useful is in clinical trials when it can help with recruitment, as well as with gathering information from patients. Mobile technology can make it easier for patients to report their experiences and keep track of any changes.

Nanotechnology

Nanotechnology is still a growing field and has a long way to go. However, there is already a lot of potential for it to be useful in a laboratory environment. Developing miniature devices and components can help with things like chemical processing. Nanomedicine can also be used alongside medications to help treat certain conditions. While there’s a limit to how quickly nanotechnology can develop, it could soon be much more useful in drug development.

New trends are technologies are changing the way drugs are developed and tested. As science advances, it should make developing new drugs safer and easier.

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Student @ Advanced Digital Sciences Center, Singapore. Travelled to 30+ countries, passion for basketball.

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Revolutionary and affordable genetic test kit identifies more than 360 DNA items

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The search for our identities—where we came from, what we’re made of—is a unifying human experience, and our collective fascination with ourselves as individuals has fueled a booming industry around personal DNA testing. Once difficult and expensive even for the most technologically advanced labs, genetic testing is fast becoming a cheap and easy consumer product. More than 12 million people have had their DNA tested by different companies, and that number is expected to grow substantially in the next few years. With a little spit and 200 dollars, you can find out your risk for everything from cystic fibrosis to lactose intolerance.

What Can I Find Out with my DNA test?

Any type of genetic testing, from the consumer-based kits that anyone can buy to the versions that doctors order, can only glean so much information from your DNA. Medical conditions like cancer and heart disease are complex and not likely to be traced to a single aberration in DNA. However, there are some genetic variants that do link to a stronger chance for certain conditions. In those cases, having the genetic change doesn’t ensure that you will develop the condition, but could mean that you have a higher chance of getting the disease.

To sort that out, a Spanish company has created its own unique chip that is able to identify more than 360 information items in the DNA, among which is the susceptibility to polygenic or complex diseases, the diagnosis of monogenic diseases, pharmacogenetic information and phenotypic traits. Thanks to this incorporation of exact biomarkers, the result of the TellmeGen’s DNA test is a 28% more accurate system, compared to than offered by other companies such as the american ‘23andMe’. This makes it a revolutionary DNA test because it offers the analysis of more items at a lower price. The goal of TellmeGen is to provide access to genetic information to people from anywhere in the world. In order to do so, they have developed a platform to store, interpret and update the genetic information when new mutations are discovered. TellmeGen is currently studying more than 555,000 mutations, and they provide this new and updated information at no additional cost.

How Does It Work?

After extracting DNA from your cheek swab or saliva sample, DNA testing companies search your DNA for certain genetic variants. The building blocks of DNA are chemical bases called nucleotides, which come in four varieties—A, T, C, and G (adenine, thymine, cytosine, and guanine, respectively). We have 3 billion pairs of these bases, so 6 billion letters in all, strung together in a sequence. Altogether, this genetic information is called your genome.

DNA testing companies determine which of the four letters is present at many locations in your genome. Much of the sequence is shared among humans, so the companies focus on specific letters that vary from person to person, known as single nucleotide polymorphisms (SNPs). Many SNPs have some biological relevance. For example, having one variant of a specific SNP near the gene OCA2, which codes for a protein believed to be involved in producing the dark pigment melanin, makes it much more likely you’ll have blue or green eyes. Other traits and even some diseases are also associated with certain SNPs, some more strongly than others.

The pioneering technology behind TellmeGen’s system is the genotyping chip, which is then analyzed in the sequencers of their many laboratories spread throughout Europe and Latin America. Thus, the system is based on scientific evidence and reaches 99.99% reliability. To get their DNA tested, all the user has to do is putting a sample of his saliva in the tube that arrives at home inside the TellmeGen Kit box and send it back to the company. You can get the DNA test on Amazon.com. Four to six weeks later, the client receives an electronic notification that his health map is already available online. In addition to the genetic information, each item in the genetic map is associated with the latest recommendations on health prevention. The users also have access to a free public forum where they can interact with medical professionals to interpret their results, and they can also hire the services of a specialist for a better interpretation of the results in an individual consultation.

How Much Does It Cost?

The idea of knowing our health’s risks in advance to be able to prevent diseases is always appealing, but the real question is: how much does a DNA test cost? TellmeGen wanted make genetic health maps affordable to everyone, and in order to do so they based their strategy on adjusting the costs. After years of previous study and analysis, they finally managed to launch TellmeGen DNA test kit, which reduces the average 3,500€ price to 199$, greatly improving the ratio items / price of any other market test.

Plus, the analysis offers four types of results in a single analysis for the same price: risk of the most common diseases, monogenic diseases, pharmacology and personal traits. In addition, in a few weeks ‘Ancestry’ will also be offered for the same price. Customers who used the kit prior to this will not have to pay more, as the results will automatically be updated for free.

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How cloud based software is revolutionizing the medical profession

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Modern clinics and surgeries are changing how they manage their administration through the use of new technology based entirely online in the cloud.  Now is the time to move away from paper based records and take advantage of the new technology that is available .

Not only will it give patients and clients a better service, but it will also increase the efficiency of the clinic and save both time and money, allowing more resource to go towards the health and well being of clients.

A better service for clients and patients, a better system for clinics

The benefits to a clinic that manages all the office and medical information through software clinic cloud are sizeable. Designed to facilitate the day to day workload of the medical professional it can manage all aspects of a clinic or medical surgery.

It allows complete electronic control over appointments and agendas, and can also provide a booking service that allows patients and clients to request their appointment online for the comfort of their own home, and can even allow them to choose the professional they would like to see. It can then be configured to send alerts to the booked professional, help avoid double booking and also helps avoid missed reservations by sending reminder emails or SMS.

Each professional at the clinic will be able to have their own user access to the program and their bookings calendar, with access permissions set to suit each users, so that they only have access to the information they need.

Not only is this software improving the booking process, it provides excellent assistance during the appointment. Full medical history of the patient is available at the click of a button, all stored in electronic format, with the ability to add information at each appointment. Some programs even have anatomical model modules that allow the recording of information in a visual way.

Streamlines accounting: Make invoices, budget, review defaults and carries a comprehensive cash control.

Improve the promotion of your business: Clinic Cloud also facilitates customer loyalty, for example through the creation of marketing campaigns by SMS.

Each professional will have their own agenda, so that the management of appointments and their payments will never have been so simple. In the same way, with the medical software you will be able to make the cash and the accounting easily.

The complete history system makes it really fast and simple: take the cards, comply with the Data Protection Law, make reports per session, and have absolute control of the patient’s account, their bonuses, and bills.

And because the software is stored in the cloud online, it is accessible from any device with an internet connection, for example on computer, tablet or smartphone. This means clinic management is simple and accessible 24/7, even when not in the office.

Not only does it hold medical records and appointment history, it can also manage billing and invoicing in a simple and easy to use way, making accounting much simpler.

Easy to use and easy to access

The great thing about cloud based software, is that it is very easy to access even for those with very little experience in software. No installation is needed, because it is stored online, and this means there are no upfront high licencing costs, cost is based on usage instead meaning clinics only have to pay for how much they use and store.

It also means not having to worry about updating the software, updates are carried out by the host without any impact on users.

Ease of access however, does not mean however that patient data is open to the world. The security of personal information is paramount, stored on servers that have the highest levels of security and comply with any data protection and privacy regulations. It is only accessible by those who have been given permission to do so, and should there ever be a problem with the host servers, the information is backed up regularly and can simply be accessed by another device.

Suitable for all types of clinics

The software available now is capable of being adapted to many different specialities.

Whether it is needed for general medicine, an aesthetic clinic, dermatology , podiatry, or dentistry all of it can be managed electronically online.

Good software will even have specialist modules, for example for dentistry to help manage that specialism.

Not only that it can also be used for targeted marketing to attract new and repeat customers through, and help drive additional revenue and footfall to the clinic with promotional campaigns.

The future of medical professionals is going to be embracing new technology, and the best way to start this is to begin managing your clinic online.

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The revolutionary way to reduce pain and risk in spine surgical procedures: Dr. Clavel’s non-invasive surgery

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Medicine is a science that evolves constantly thanks to elite professionals who dedicate their lives to develop new techniques aimed to improve people’s health in the easiest –and less painful way possible. One of these top doctors is Dr. Clavel, a surgeon who believes that surgery is an art capable of transforming lives… And his work proves him right. This valuable health professional stands out in the neurosurgery field, a specialty that has been developing greatly in recent decades. However, most of its success stems from its advances in spinal surgery in patients with serious low back pain.

What is non-invasive lumbar surgery?

Invasive spinal surgeries have always been considered high-risk interventions because there are various anatomical structures that must be avoided prior reaching the affected area of the spine. Most spine surgical procedures —such as arthrodesis, fixation and fusion, require long back incisions, large muscle dissection and manipulation of nerve structures. All of these techniques can lead to significant blood loss, nerve injuries, muscle atrophy and ulterior chronic pain.

Since this was the only known technique to deal with these issues, Dr. Clavel decided to focus his research on improving traditional surgery methods to treat herniated discs or other physical difficulties lodged in the lumbar area, such as degeneration. His years of dedication led him to further deepen in the field of non-invasive anterior lumbar surgery: Non-invasive lumbar surgery. This revolutionary technique uses an anterior approach to perform the surgery. Thus, there is no need to manipulate or mobilize muscles nor nerves, so there is less risk of injuries. Plus, this kind of surgery does not require to perform osteotomies to introduce implants — which eliminates vertebral destabilization and blood loss, nor opening the back muscles. This translates in a safer intervention and less postoperative pain long term

The non-invasive lumbar surgery Performed by Dr. Clavel, represents a fundamental advance in the field of spinal surgery. It has been demonstrated that this surgical procedure would avoid the classic difficulty of common surgical-lumbar processes, in which bone structures must be destroyed –which means a high probability of damaging an important nerve. By accessing www.barcelonaspinecenter.com you will be able to find more detailed information related to this type of intervention, and the possibility of opting for a medical and surgical assessment.

Doctor Clavel, a leading expert

Pablo Clavel began working as a neurosurgeon in the city of Barcelona in 1995 after being trained in different American universities such as Emory University in Atlanta, Oklahoma University and San Diego University. After years of  experience in various private and public hospitals and teaching Neurosurgery courses at Cornell Hospital in New York,  ​​Dr. Clavel founded Instituto Clavel (Barcelona Spine Center) and he has been head of the Neurosurgery and Column Department since 2011.

Doctor Clavel is also an example of professionalism and vocation: despite his 20 years of professional experience, he keeps educating himself in order to achieve and develop the best surgery techniques. He combines the performance of spine surgery with research and teaching activities: he has published several relevant articles in scientific journals, and he is currently teaching courses and giving conferences about spine surgery worldwide.  He is also a medical advisor to Neosurgery SL, a company dedicated to researching and developing implantable medical devices in neurosurgery.

In addition to his work as a neurosurgeon Dr. Clavel also performs as a volunteer neurosurgeon in African countries such as Ethiopia, where the charity that he founded (Fundación Doctor Clavel) is currently training local doctors and nursing staff in neurosurgery procedures.

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